Module Advanced Genetics
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Location Penrith - Newton Rigg
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Duration Single module
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Mode of study Full-time, Part-time
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Start date September 2012
What can this course lead to?
Please note: Existing University of Cumbria students need to email absadmissons@cumbria.ac.uk in order to apply. They do not need to go through the full application process.
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Critically evaluate the application of gene cloning and expression technology to molecular genetics.
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Demonstrate comprehensive knowledge of the application of molecular genetics in the detection and diagnosis of disease
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Critically evaluate the scope and limitations of advanced molecular genetics techniques.
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Critically evaluate and assess the ethical implications concerning the development of transgenic organisms.
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Analyse, interpret and critically evaluate data using techniques appropriate to the subject matter.
Course Summary
This module will discuss the application of molecular genetics to medical research, forensic science, clinical diagnostics and disease treatment as well as providing an overview of current biotechnological advances.
Indicative Student Workload
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Lectures
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24 Hours
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Practical sessions
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6 Hours
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Student directed learning
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170 Hours
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Assessment Plan
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Method of Assessment
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Wordage/Hourage
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ILOs Assessed
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Weighting (%)
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Examination
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2 hours
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1-5
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50
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Essay
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2500 words
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2,3
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50
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Both forms of assessment must be passed.
Modules
The module will cover the following areas: -
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Gene cloning and expression studies – the use of bacterial vectors and hosts, selection and screening procedures and the construction of vectors and libraries.
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Current Polymerase chain techniques – RT-PCR, PCR mutagenesis.
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Screening and separation techniques – the labelling of nucleic acids, immunofluorescence, Southern, Western and Northern Blotting and micro-array technology.
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Recombinant proteins – reporter genes, vaccine technology, engineered antibodies and their application, proteins as therapeutic agents and the use of bacteria to manufacture HGH and insulin.
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Genetically Modified Organisms – transgenic plants and animals (development of increased plant yield and disease resistance).
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Genome Project - the commercialisation of genetic information, gene therapy and single nucleotide polymorphisms (SNPs) as indicators of susceptibility.